Australian wheelchair tennis champion Dylan Alcott has secured an unprecedented men's Golden Slam tennis sweep after winning the US Open Quad title.

The Golden Slam takes in his Australian, French, Wimbledon and now US Open Championships, together with his gold medal from the Tokyo Paralympic Games.

Alcott defeated Dutchman Niels Vink in straight sets at Flushing Meadows, 7-5, 6-2.

"I can't believe I just won the Golden Slam," Alcott said following his win.

"I used to hate myself so much, I hated my disability, I didn't even want to be here any more.

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"I found tennis and it changed and saved my life.

"Now I've become the only male ever in any form of tennis to win the Golden Slam which is pretty cool."

He thanked the organisers for "putting us on stadium courts, changing my life, changing Niels's life, and giving disabled people a platform."

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Alcott celebrated with supporters, then turned up next door at the Arthur Ashe Stadium to watch the men's singles final between Novak Djokovic and Daniil Medvedev.

As the cameras pointed at him in the stands, the Australian opened a can of beer, poured it in his US Open trophy and drank, then tipped the trophy on top of his head, prompting big cheers from the Flushing Meadows crowd.

The match immediately prior to Alcott's, saw women's tennis champ Diede De Groot of the Netherlands clinch the women's Golden Slam in New York.

She beat Yui Jamiji of Japan 6-3, 6-2 to win the US Open wheelchair women's singles (open division) title.

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DeGroot was the first tennis player to win all four major titles plus a gold medal in the same year since Steffi Graf in 1988.