Australia is in a strong position on day two of the second Test against West Indies in Adelaide, reducing the tourists to 4-102 after declaring on 7-511.

Marnus Labuschagne (163) and Travis Head (175) made 297 together for the fourth wicket to set up Australia's declaration shortly before the tea break, just as the lights began to take affect at Adelaide Oval.

With the new pink ball moving off the seam, West Indies toiled through the final session under lights, ending the day 409 runs behind and with any hope of salvaging something from the series rapidly evaporating.

Australia has won all 10 of its day-night pink-ball Test matches and showed why thanks to another potent display of bowling under lights.

Where West Indies struggled to make inroads, Australia's battery of seam options tortured their opponents with probing lengths and lines.

Michael Neser claimed the wickets of Kraigg Brathwaite (19) and Shamarh Brooks (8), both caught behind by Alex Carey after tea.

Neser was superb and fully deserved making the double breakthrough, but Scott Boland was equally impressive as Australia's stand-in seamers proved they were up to the task, just as they were 12 months earlier when injury forced their call-ups to the Ashes squad.

Mitchell Starc — with 56 — has more wickets in pink-ball Tests than anyone else, but was unable to prise an opening in either of his two spells.

However, Nathan Lyon — second on the list with 34 heading into this match — was.

Lyon claimed his 57th Test wicket at Adelaide Oval — passing Shane Warne for the most prolific wicket-taker at the storied venue — with a sharp caught and bowled chance to dismiss Jermaine Blackwood (3).

Devon Thomas and Tagenarine Chanderpaul regrouped with a 40-run fourth wicket partnership until Cameron Green claimed the crucial wicket of Thomas for 19 as part of an eight-ball first over that had gone for a whopping 17 runs.

Anderson Phillip was sent in as night watchman with 15 minutes to play and did his job, absorbing 17 balls under serious pressure.

Chanderpaul, who had started to play his shots as the close approached, ended the day just three runs shy of a second Test half-century in his second Test.

Earlier in the day, Labuschagne and Head continued to plunder the ineffective West Indies attack throughout the opening session.

Neither man looked troubled as both made their way past 150 in consecutive overs.