Tim Tszyu will fight for a world title against Tony Harrison in Australia, 20 years after his father did it for the final time.

The Sydney product has locked in a March 12 meeting with American Harrison for the WBO super welterweight world title, with the city and venue still to be confirmed.

Tszyu (21-0, 15KO) has remained in his United States camp since a January 28 dream shot at Jermell Charlo was put on ice, the undisputed champion breaking his hand in training in December.

It has left the 28-year-old fighting for one belt instead of all of them and it will be a stiff task against Detroit product Harrison (29-3-1, 21KO), the only man to ever beat Charlo, winning a unanimous decision in 2018.

The now-32-year-old earned the WBC belt in 2018 but then immediately handed it back to Charlo in a rematch.

Gold Coast, Sydney and Melbourne are reportedly in a race to host the Sunday afternoon spectacle.

Nikita Tszyu will also fight on the same card as his older brother for the first time, while father and former Australian boxing great Kostya — who defended three belts against Jesse James Leija in Melbourne in 2003 — will be a keen spectator.

"I think Australia is going to erupt," Tszyu said in a statement on Monday, confirming his first fight in Australia for almost 18 months.

"It's a massive fight for Australia and a special moment in my career.

"But his biggest problem he's running into isn't the fans, it's me."

The winner will claim the interim title and face a fit-again Charlo for all four belts later this year.

Harrison is ranked number two by the WBC, number three by the WBO and was in a race with undefeated Russian Bakhram Murtazaliev to face Tszyu and create an avenue of their own to Charlo's belts.

"Every fight you take is all on the line, you're one punch away from going back to the very bottom," Tszyu said of the risk the fight poses.

"It's all on the line and a gamble, but this is what I do. This is boxing, it's part of my career and I'm a fighter first.