Australia's Alex de Minaur has raced into the US Open third round like he had a hot ticket to Broadway.

The world number 13 dispatched Yibing Wu 6-1, 6-2, 6-1 in just 86 minutes to storm into the last 32 for the fifth time in seven trips to New York.

A quarterfinalist in 2020, de Minaur loves the faster pace of Flushing Meadows and sped through Thursday's match in vastly different fashion to his laborious four-set, first-round dogfight against Kazakh qualifier Timofey Skatov.

In typical fashion, the Australian was not heavy on hitting winners, but gave up just 10 unforced errors in a solid performance.

De Minaur also put huge pressure on Wu's serve, setting up 18 break points and taking seven of those opportunities.

Wu is the Chinese giant-killer who not only dumped Nick Kyrgios out of Stuttgart in the grand slam finalist's premature return from a knee injury this year but also up-ended Denis Shapovalov and Taylor Fritz en route to the final on Dallas hard courts in February.

But de Minaur broke him seven times, won 82 per cent of his first-serve points and committed a meagre 10 unforced errors in 22 games to join countryman Rinky Hijikata in the last 32.

The 13th seed will play either Chile's world number 25 Nicolas Jarry or 17-year-old American wildcard Alex Michelsen on Sunday (AEST) for a place in the last 16 of the season's final major.

Wildcard Hijikata is up against China's world number 67 Zhizhen Zhang on Friday (Saturday AEST) in his first grand slam third-round appearance.