Australia has wrapped up the three-game ODI series against West Indies with another big win, chasing down just 104 to win inside 16 overs in St Kilda.

It means the world champion Australians win the 50-over series 2-0, after game two was rained out, after winning two of three Twenty20 clashes against the same side.

Captain Alyssa Healy led the way in the run chase with 32 off 27, but the work was done by the bowlers, who skittled West Indies for just 103 at Junction Oval.

The tourists lost rookie opener Zaida James for a 15-ball duck and captain Hayley Matthews (23 off 17) in the powerplay, and veteran Stafanie Taylor (4) followed them back to the sheds soon after.

In the 12th over, Taylor chipped a ball back at seamer Annabel Sutherland, who stuck a hand down to her bootlaces to take a phenomenal grab, with the third umpire ruling the ball had carried on the full despite replays suggesting it may have hit the ground.

Taylor shook her head in disbelief after third umpire Claire Polosak confirmed the caught-and-bowled dismissal.

It sparked a collapse of 4-9 in 14 balls and the tail just barely managed to drag the team into three figures, leaving Australia a victory target of 104.

Making matters worse for Taylor, she was tossed the ball for her first and only over with Australia just 14 runs from victory.

Aided by a wide and a no ball, Ellyse Perry (29 off 21) and Beth Mooney (11 off 17) scored 15 runs off three legitimate deliveries, including Perry's six to win the game.