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The Bupa Health Foundation awarded a grant for a research proposals that looks to predict response to memory-enhancing drugs for people with dementia using brain imaging techniques, delivering individualised care to improve outcomes for people with Alzheimer’s disease.
This study will investigate whether measuring brain function associated with memory in people with early dementia can predict their response to cholinesterase inhibitors, medicines that may enhance cognitive function and stabilise memory. Imaging techniques (PET and MRI) will be used to measure the function of specific (cholinergic) nerves in the brain, to help doctors decide whether to prescribe the cholinesterase inhibitors. This individualised treatment could improve outcomes for people with Alzheimer’s disease.