“It was a challenging road for me, the baby-making road,” the Friends star told Allure in 2022. “All the years and years of speculation... it was really hard. I was going through IVF, drinking Chinese teas, you name it.”

She added: “I would’ve given anything if someone had said to me, ‘Freeze your eggs. Do yourself a favour.’ You just don’t think it. So here I am today. The ship has sailed.”

Vance’s comments lead to backlash

Earlier this week, Pete Buttigieg, the US transportation secretary, who was also singled out by Mr Vance in his “cat lady” remark, responded to the comments.

Mr Buttigieg, who is a father to twins he adopted with his husband Chasten, told CNN: “The really sad thing is he said that after Chasten and I had been through a fairly heartbreaking setback in our adoption journey.

“He couldn’t have known that – but maybe that’s why you shouldn’t be talking about other people’s children.”

Meghan McCain, the daughter of John McCain, late Republican senator, said that Mr Vance’s comments were “activating” even to the most conservative Trump-supporting women.

Ella Emhoff, Ms Harris’ stepdaughter, also fired back to Mr Vance. “How can you be ‘childless’ when you have cutie pie kids like Cole and I,” she posted on Instagram, sharing an earlier statement by her biological mother, Kerstin Emhoff, praising Ms Harris role as a “loving” and “nurturing” co-parent.

The Telegraph