A man has been shot dead and at least five more people are in hospital following a massive brawl south-west of Brisbane.

A fight between about 15 people, which was believed to have involved a car, a gun and a baseball bat, broke out in Ipswich about 5pm on Tuesday.

Four men were taken from the scene to hospital but one died from gunshot wounds.

9News understands paramedics were also called to a nearby home before taking two men, one with a gunshot wound, to hospital.

Police remained on the scene on Tuesday night trying to piece together what happened and track down the others involved in the fight.

Anyone with information should contact Crime Stoppers on 1800 333 000.